Neuropathy in Non-Freezing Cold Injury (Trench Foot)

Trench Foot or Non-Freezing Cold Injury As a Painful Vaso-Neuropathy: Clinical and Skin Biopsy Assessments

BACKGROUND Trench foot, or non-freezing cold injury (NFCI), results from cold exposure of sufficient severity and duration above freezing point, with consequent sensory and vascular abnormalities which may persist for years. Based on observations of Trench foot in World War II, the condition was described as a vaso-neuropathy. While some reports have documented nerve damage after extreme cold e...

Cold still kills: cold-related illnesses in military practice freezing and non-freezing cold injury.

Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy

Non-freezing cold injury develops after sustained exposure to cold temperatures, resulting in tissue cooling but not freezing. This can result in persistent sensory disturbance of the hands and feet including numbness, paraesthesia and chronic pain. Both vascular and neurological aetiologies of this pain have been suggested but remain unproven. We prospectively approached patients referred for ...

Non-freezing cold injury: a multi-faceted syndrome.

We read the paper “Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy” by Vale and colleagues recently published in Brain with great interest. Despite the impact non-freezing cold injury (NFCI) can have on an individual’s quality of life, little research has been conducted on this condition. Indeed, in the last 10 years only 16 full papers have been publish...

Clinical Aspects of Freezing Cold Injury